Christian Hamann

Research Associate

Chris Hamann

Contact & Office Hours

Ford Hall 344



Ph.D., University of Pennsylvania

B.S., Lebanon Valley College


Christian Hamann is a physical organic chemist who applies a variety of techniques to propose and investigate models for the biosynthesis of terpenes, a class of secondary metabolites that are found in all known organisms. Current molecules of interest include humulene (one of the flavoring agents in Humulus lupulus, beer hops) and seychellene (a fragrant oil from Pogostemon cablin, patchouli). Work in this area has led to computational studies on atropisomeric systems, chiral molecules with no chiral centers that interconvert via a series of conformational changes. Further, his laboratory has developed a successful approach to organizing computational data from terpene conformation experiments that supports research productivity with a searchable database of experimental results from several research groups.

Hamann also develops teaching methods and laboratory experiments that provide students with meaningful learning experiences that support both in-course success and long-term, positive educational outcomes. Other areas of interest include undergraduate research (he was recently elected to the Council on Undergraduate Research) and promoting opportunities for chemists with disabilities (in addition to publishing in this area, he is an associate member of the Committee on Chemists with Disabilities of the American Chemical Society).

Recent Publications

*(formerly) undergraduate student co-authors

Using Esters to Construct Chemical Shift Correlation and Introduce First-Order Coupling. Smith, KT*; Hamann, CS. Journal of Chemical Education (2017) 94, 126-130.

Utilizing NMR to Study Structure and Equilibrium in the Organic Chemistry Laboratory. Smith, KT*; Young, SC*; DeBlasio, JW*; Hamann, CS. In NMR Spectroscopy in the Undergraduate Curriculum: First Year and Organic Chemistry Courses Volume 2; Soulsby, D., Anna, L. J., Wallner, A. S., Eds.; ACS Symposium Series 1221; American Chemical Society: Washington, DC, 2016; pp 119-136.

Measuring Structural and Electronic Effects on Keto-enol Equilibrium in 1,3-Dicarbonyl Compounds. Smith, KT*; Young, SC*; DeBlasio, JW*; Hamann, CS. Journal of Chemical Education (2016) 93, 790-794.

Predicting Hydration Propensities of Biologically Relevant α-Ketoamides. Wedler, HB*; Palazzo, TA; Pemberton, RP; Hamann, CS; Kurth, MJ; Tantillo, DJ. Bioorganic and Medicinal Chemistry Letters (2015) 25, 4153-4157.

Delocalization of Charge and Electron Density in the Humulyl Cation—Implications for Terpene Biosynthesis. Hamlin, TA*; Hamann, CS; Tantillo, DJ. Journal of Organic Chemistry (2015) 80, 4046-4053.

Nobody Can See Atoms: Science Camps Highlighting Approaches for Making Chemistry Accessible to Blind and Visually-Impaired Students. Wedler, HB*; Boyes, L; Davis, RL; Flynn, D; Franz, A; Hamann, CS; Harrison, JG; Lodewyk, MW; Milinkevich, KA; Shaw, JT; Tantillo, DJ; Wang, S.C. Journal of Chemical Education (2014) 91, 188-194.

Applied Computational Chemistry for the Blind and Visually Impaired. Wedler, HB*; Cohen, SR; Davis, RL; Harrison, JG; Siebert, MR; Willenbring, D; Hamann, CS; Shaw, JT; Tantillo, DJ. Journal of Chemical Education (2012) 89, 1400-1404.