Alexis Ziemba

Postdoctoral Fellow and Lecturer in Neuroscience

she/her

Smith College

Contact & Office Hours

Biography

Alexis Ziemba is a neural engineer whose work spans targeted drug delivery to the nervous system, neural regeneration, neuroinflammation, and neuropharmacology. Her current research is in collaboration with the Moore and Buck labs at Smith College. This team is developing protein-polymer conjugates to selectively target/treat cancers of the brain as well as developing regenerative hydrogel scaffolds for peripheral nerve injury applications. Alexis also teaches interdisciplinary courses centered around cellular and molecular neuroscience and targeted drug delivery to the central nervous system.

Selected Publications

(*indicates undergraduate co-author, #indicates equal author contribution)

JL Funnell, AM Ziemba, JF Nowak, H Awada, N Prokopiou*, J Samuel, Y Guari, B Nottelet, RJ Gilbert (2021) Assessing the combination of magnetic field stimulation, iron oxide nanoparticles, and aligned electrospun fibers for promoting neurite outgrowth from dorsal root ganglia in vitro. Acta Biomaterialia 131, 302-313.

AM Ziemba#, TD Fink#, MC Crochiere*#, DL Puhl, S Sapkota*, RJ Gilbert, Zha RH (2020) Coating topologically complex electrospun fibers with nanothin silk fibroin enhances neurite outgrowth in vitro. ACS Biomaterials Science & Engineering 6 (3), 1321-1332.

CM Zajd#, AM Ziemba#, GM Miralles, T Nguyen, PJ Feustel, SM Dunn, RJ Gilbert, MR Lennartz (2020) Bone Marrow-Derived and Elicited Peritoneal Macrophages are not Created Equal: The Questions Asked Dictate the Cell Type Used. Frontiers in Immunology 11, 269

AM Ziemba, AR D'Amato, TM MacEwen*, DL Puhl*, AN Koppes, RA Koppes, MR Lennartz, RJ Gilbert (2019) Stabilized interleukin-4-loaded poly (lactic-co-glycolic) acid films shift pro-inflammatory macrophages towards a regenerative phenotype in vitro. ACS Applied Bio Materials 2(4)1498–1508.

AM Ziemba, A Szabo, DW Pierce, M Haburcak, AT Stern, A Nourmahnad, ES Halpin, SA Forman (2018) Alphaxalone Binds in Inner Transmembrane β+–α− Interfaces of α1β3γ2 γ-Aminobutyric Acid Type A Receptors. Anesthesiology 128 (2), 338-351

AM Ziemba, SA Forman (2016) Correction for Inhibition Leads to an Allosteric Co-Agonist Model for Pentobarbital Modulation and Activation of α1β3γ2L GABAA Receptors. PloS one 11 (4), e0154031.

To view additional studies, please visit google scholar.